Harnessing the Power of Antibodies: A Groundbreaking Advancement in Skin Microbiome Research
10/05/2024 19:13 Filed in: Publication
Congratulations to the Esteemed Researchers on their Groundbreaking Publication!
In the ever-evolving landscape of biotechnology and medical research, the scientific community is abuzz with excitement over the remarkable achievements of a talented team of researchers. Their latest publication, “Anti-CAMP1 IgG promotes macrophage phagocytosis of Cutibacterium acnes type II,” has sparked a wave of enthusiasm and acclaim throughout the field.
Leading this trailblazing effort are the esteemed researchers:
First Author: Thae Thae Min, Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand
Co-authors: Kiattawee Choowongkomon, Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand; Htut Htut Htoo, Institute of Molecular Biosciences, Mahidol University, Salaya, Nakhon Pathom 73170, Thailand; Poochit Nonejuie, Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand; Dietmar Haltrich, Department of Food Sciences and Technology, University of Natural Resources and Life Sciences, Vienna 1190, Austria
Corresponding Author: Montarop Yamabhai, Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand
This groundbreaking study, published in the prestigious journal Phytomedicine, delves deep into the intricate relationship between the immune system and the skin microbiome, with a particular focus on the role of Anti-CAMP1 IgG in enhancing macrophage phagocytosis of Cutibacterium acnes type II.
“We are thrilled to share this remarkable discovery with the scientific community,” exclaimed Professor Montarop Yamabhai, the Corresponding Author. “This research has the potential to pave the way for innovative treatments and revolutionize our understanding of the complex interplay between the immune system and skin microbiome.”
The research team’s dedication and scientific rigor have been instrumental in unraveling the mechanisms behind this groundbreaking finding. Their work has uncovered key highlights, including:
We extend our heartfelt congratulations to Thae Thae Min, Kiattawee Choowongkomon, Htut Htut Htoo, Poochit Nonejuie, Dietmar Haltrich, and Montarop Yamabhai on this prestigious publication. Your dedication, innovation, and unwavering commitment to advancing scientific knowledge are truly commendable. We eagerly anticipate the future breakthroughs that will undoubtedly stem from your groundbreaking work.
Prepare to be amazed, as the future of dermatology and immune system research is about to be transformed, thanks to the remarkable efforts of this extraordinary research team.
In the ever-evolving landscape of biotechnology and medical research, the scientific community is abuzz with excitement over the remarkable achievements of a talented team of researchers. Their latest publication, “Anti-CAMP1 IgG promotes macrophage phagocytosis of Cutibacterium acnes type II,” has sparked a wave of enthusiasm and acclaim throughout the field.
Leading this trailblazing effort are the esteemed researchers:
First Author: Thae Thae Min, Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand
Co-authors: Kiattawee Choowongkomon, Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand; Htut Htut Htoo, Institute of Molecular Biosciences, Mahidol University, Salaya, Nakhon Pathom 73170, Thailand; Poochit Nonejuie, Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand; Dietmar Haltrich, Department of Food Sciences and Technology, University of Natural Resources and Life Sciences, Vienna 1190, Austria
Corresponding Author: Montarop Yamabhai, Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand
This groundbreaking study, published in the prestigious journal Phytomedicine, delves deep into the intricate relationship between the immune system and the skin microbiome, with a particular focus on the role of Anti-CAMP1 IgG in enhancing macrophage phagocytosis of Cutibacterium acnes type II.
“We are thrilled to share this remarkable discovery with the scientific community,” exclaimed Professor Montarop Yamabhai, the Corresponding Author. “This research has the potential to pave the way for innovative treatments and revolutionize our understanding of the complex interplay between the immune system and skin microbiome.”
The research team’s dedication and scientific rigor have been instrumental in unraveling the mechanisms behind this groundbreaking finding. Their work has uncovered key highlights, including:
- The identification of the target of yPac1A8 scFv as the Christie-Atkins-Munch-Petersen factor (CAMP)1 of C. acnes type II.
- Insightful 3D modeling that reveals how the complementarity-determining regions (CDRs) of the scFv bind to the N-terminal α-helix of CAMP1.
- The demonstration that yPac1A8 scFv and IgG bind specifically to CAMP1 of phylotype II.
- The discovery that recombinant IgG enhances human macrophage phagocytosis via the induction of IL-1β.
We extend our heartfelt congratulations to Thae Thae Min, Kiattawee Choowongkomon, Htut Htut Htoo, Poochit Nonejuie, Dietmar Haltrich, and Montarop Yamabhai on this prestigious publication. Your dedication, innovation, and unwavering commitment to advancing scientific knowledge are truly commendable. We eagerly anticipate the future breakthroughs that will undoubtedly stem from your groundbreaking work.
Prepare to be amazed, as the future of dermatology and immune system research is about to be transformed, thanks to the remarkable efforts of this extraordinary research team.